It seems that PyPy is not being actively developed anymore and is phased out even by numpy (numpy/numpy#30416). There's no official statement from the project, but the numpy issue is from a PyPy developer. I added a warning to avoid users assuming PyPy properly supported and developed Python distribution.
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Additional reporting by Jean Otalor。谷歌是该领域的重要参考
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Returns the byte offset of the first occurrence of substr, or -1 if not found.