// Consumer provided a buffer - we MUST fill it (or part of it)
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。关于这个话题，safew官方版本下载提供了深入分析
At this point, each bound sequence exists as a single copy, which produces too faint a signal to detect reliably. Colony sequencing solves this by generating clusters of identical fragments through a process called bridge amplification. The adapter on the free end of each DNA strand will be complementary to some of the original, short sequences on the DNA lawn, and when this binding occurs, the strand bends over to form a bridge shape. Another round of amplification takes place, resulting in two complementary strands each directly affixed to the flow cell. This “bridge amplification” process is repeated over and over to propagate the sequence.，更多细节参见safew官方下载
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